SMPD1 / ASM Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16263-20, A16263-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 70kDa
Observed Molecular Weight: 75kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6609
SWISS: P17405
Alternate Names: ASM; NPD; ASMASE; SMPD1 / ASM
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Lipid Metabolism, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: SMPD1
Research Use Only