Product Description

SMYD5 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7955-50, BS7955-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3 which represents a specific tag for epigenetic transcriptional repression (By similarity. In association with the NCoR corepressor complex, is involved in the repression of toll-like receptor 4 (TLR4-target inflammatory genes in macrophages by catalyzing the formation of H4K20me3 at the gene promoters (By similarity. Plays an important role in embryonic stem (ES cell self-renewal and differentiation (By similarity. Promotes ES cell maintenance by silencing differentiation genes through deposition of H4K20me3 marks (By similarity. Maintains genome stability of ES cells during differentiation through regμlation of heterochromatin formation and repression of endogenous repetitive DNA elements by depositing H4K20me3 marks.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, IF/ICC

Alternate Names: SMYD5, NN8-4AG, RAI15, RRG1, ZMYND23

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human SMYDSMYD5

Dilution: WB, 1:500 - 1:2000 IHC, 1:50 - 1:200 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 48kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6GMV2

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only