Product Description

SNAI2 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16516-50, BZ16516-100

Swiss-Prot: O43623

Host: Rabbit

SNAI2 Polyclonal Antibody-BZ16516

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 30 kDa; Observed MW: 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SNAI2 in MCF-7, mouse Heart, rat Heart, rat BrainLysates using SNAI2 antibody., Immunohistochemistry analysis of paraffin-embedded Human Breast caricnoma using SNAI2 antibody High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: SNAI2; SLUG; SLUGH; Zinc finger protein SNAI2; Neural crest transcription factor Slug; Protein snail homolog 2

Immunogen: Recombinant Protein of SLUG

Modification: Unmodified

Conjugate: Unconjugated