SNF5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91264-50, BS91264-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q12824(Human) Q9Z0H3(Mouse)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC FC
All Applications: WB:1:500-1:1,000
IHC:1:50-1:100
FC:1:50-1:100
Background: The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: SNF5 polyclonal antibody detects endogenous levels of SNF5 protein.
Bioworld Molecular Weight: 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of SNF5 on Daudi cell and mouse lymph node tissue lysates using anti-SNF5 antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-SNF5 antibody. Counter stained with hematoxylin.
Alternative Name: BAF47, hSNF5, SMARCB1, BAF47, INI1, SNF5L1, BAF47, BRG1-associated factor 47, hSNF5, INI1, Integrase interactor 1 protein, Malignant rhabdoid tumor suppressor, RDT, RTPS1, Sfh1p, SMARCB1, SNF5 homolog, SNF5, SNF5L1, Snr1, Sucrose nonfermenting yeast homolog like 1, SWI/SNF complex component SNF5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI10, Transcription factor TYE4, Transcription regulatory protein SNF5, TYE4,
Immunogen: Synthetic peptide of C terminal Human SNF5.
Conjugate: Unconjugated
Modification: Unmodified