Product Description

SnoN Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29935-50, RA29935-100

Citations, Manuals and MSDS Available upon request.

Background: SKI like proto-oncogene (SKIL) Homo sapiens The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB) . In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: SKIL; SNO; Ski-like protein; Ski-related oncogene; Ski-related protein

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 6498

Protein MW (KDa): 77

SWISS: P12757

Source: Rabbit

Research Use Only