Product Description

SNRPB Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8064-50, BS8064-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P14678

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Background: mRNA precursors are processed in the spliceosome, where introns are excised to form continuous coding sequences. The major components of the spliceosome are RNA-protein complexes called snRNPs (small nuclear ribonucleoprotein particles). The core proteins that are common to all snRNPs are called the Sm proteins, and are designated B, B’, D1, D2, D3, E, F and G. Antibodies recognizing Sm proteins are frequently generated in autoimmune diseases, including in patients with systemic lupus erythematosus. Sm proteins are characterized by a conserved Sm sequence motif in two parts, Sm1 and Sm2, which are separated by a variable region.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SNRPB polyclonal antibody detects endogenous levels of SNRPB protein.

Bioworld Molecular Weight: ~ 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using SNRPB antibody at 1:3000 dilution.

Alternative Name: Small nuclear ribonucleoprotein-associated proteins B and B'; snRNP-B; Sm protein B/B'; Sm-B/B'; SmB/B'; SNRPB; COD; SNRPB1

Immunogen: Recombinant full length Human SNRPB.

Conjugate: Unconjugated

Modification: Unmodified