SNX13 rabbit pAb - ES13032

SNX13 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES13032-50, ES13032-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],

Alternate Name: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)

Source: Rabbit

Applications: WB

Dilution: WB 1:500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human SNX13 AA range: 602-652

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 105kD

Human Gene ID: 23161

Human SWISS Prot NO: Q9Y5W8

Subcellular Location: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.

Research Use Only