Product Description

SNX13 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34930-50, RA34930-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)

Clonality: Polyclonal

Dilution: WB 1:500-2000

Molecular Weight: 105

Protein Molecular Weight (kDa): 105

Storage: -20°C/1 year

Human Gene ID: 23161

Human SwissProt Number: Q9Y5W8

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.

Research Use Only