SNX13 Rabbit Polyclonal Antibody - RA34930

SNX13 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34930-50, RA34930-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha (s), accelerates its GTP hydrolysis, and attenuates G alpha (s) -mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 23161

Protein MW (KDa): 105

SWISS: Q9Y5W8

Source: Rabbit

Research Use Only