Socius Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29947-50, RA29947-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: UBX domain protein 11 (UBXN11) Homo sapiens This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, IHC-p, IF/ICC, ELISA Alternate Names: UBXN11, SOC, UBXD5, PP2243, UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 57 Protein Molecular Weight (kDa): 57 Storage: -20°C/1 year Human Gene ID: 91544 Human SwissProt Number: Q5T124 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only