Product Description

SOCS-1 Mouse Monoclonal Antibody (5C3)

Sizes: 50μL, 100μL

Catalogue Numbers: RA12012-50, RA12012-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: suppressor of cytokine signaling 1 (SOCS1) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IHC-p, WB

Alternate Names: Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)

Clonality: Monoclonal

Dilution: IHC-p1:50-200, WB 1:1000-2000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.53% sodium azide.

Human Gene ID: 8651

Protein Molecular Weight（KDa): 23

Molecular Weight: 23

Research Use Only