SOCS-1 Mouse Monoclonal Antibody (5C3) - RA12012

SOCS-1 Mouse Monoclonal Antibody (5C3)

Size: 50μL, 100μL

Catalogue Numbers: RA12012-50, RA12012-100

Citations, Manuals and MSDS Available upon request.

Background: suppressor of cytokine signaling 1 (SOCS1) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.53% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC-p; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 8651

Protein MW (KDa): 23

SWISS: O15524

Source: Mouse

Research Use Only