Product Description

SOCS-3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA12013-50, RA12013-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: suppressor of cytokine signaling 3 (SOCS3) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Mouse

Applications: WB, IHC-p, IF(paraffin section)

Alternate Names: SOCS3, CIS3, SSI3, Suppressor of cytokine signaling 3, SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SSI-3

Clonality: Monoclonal

Dilution: Western Blot: 1/1000 - 1/2000. Immunohistochemistry: 1/500 - 1/1000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Human Gene ID: 9021

Research Use Only