SOD-1 Polyclonal Antibody - BT-AP08448

SOD-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08448-20, BT-AP08448-50, BT-AP08448-100

Citations, Manuals and MSDS Available upon request.

Background: Superoxide dismutase [Cu-Zn] encoded by SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Research Areas: Signal Transduction

Target Protein: SOD1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SOD-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 15936

UniProt Accession: Human: P00441; Mouse: P08228; Rat: P07632

Synonyms: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

GeneID: Human: 6647; Mouse: 20655; Rat: 24786

Research Use Only