SOD1 rabbit pAb - ES20629

SOD1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20629-50, ES20629-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Source: Rabbit

Applications: WB; IHC; IF

Dilution: Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from the Internal region of human SOD-1.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Observed Band (KD): 18kD

Human Gene ID: 6647

Human SWISS Prot NO: P00441

Subcellular Location: Cytoplasm. Mitochondrion. Nucleus. Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.

Research Use Only