SOD2 Polyclonal Antibody - BT-AP14364

SOD2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14364-20, BT-AP14364-50, BT-AP14364-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Research Areas: Signal transduction; Neuroscience; Cell biology; Metabolism; Cancer

Target Protein: SOD2

Applications: WB, IHC-p, IF

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Superoxide dismutase [Mn], mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P04179; Mouse: P09671; Rat: P07895

Synonyms: Superoxide dismutase [Mn], mitochondrial; SOD2; Superoxide dismutase [Mn; , mitochondrial

GeneID: Human: 6648

Research Use Only