Product Description

SOX1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91270-50, BS91270-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O00570(Human) P53783(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC/IF, IHC

All Applications: WB:1:500-1:1,000
ICC:1:50-1:100
IHC:1:50-1:100

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining SOX1 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0. 25% Triton X100/PBS.

Bioworld Molecular Weight: 39 kDa

Specificity: SOX1 polyclonal antibody detects endogenous levels of SOX1 protein.

Alternative Name: SOX1, Sex determining region Y box 1, sox1, SOX1, SRY, SRY box containing gene 1, SRY related HMG box gene 1, Transcription factor Sox-1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified