Product Description

SOX18 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91274-50, BS91274-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P35713(Human) P43680(Mouse) EntrezGene:311723(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB:1:1,000
IHC:1:50-1:200

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SOX18 on K562 cellsLysates using anti-SOX18 antibody at 1/1,000 dilution.

Bioworld Molecular Weight: 41 kDa

Specificity: SOX18 polyclonal antibody detects endogenous levels of SOX18 protein.

Alternative Name: SOX18, HLTS, SOX 18, Sox18, SOX18, SRY (sex determining region Y) box 18, SRY box 18, Transcription factor SOX 18, Transcription factor SOX-18,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified