Product Description

SOX2 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40094-50, BS40094-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P48431

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC, ICC/IF

All Applications: WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SOX2 Antibody detects endogenous levels of total SOX2

Bioworld Molecular Weight: 34kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SOX2 expression in (1) NCCIT cell lysate; (2) F9 cell lysate., Immunohistochemical analysis of paraffin-embedded human cervix carcinoma, using SOX2 Antibody., Immunofluorescent analysis of NCCIT cells, using SOX2 Antibody.

Alternative Name: SOX2; ANOP3; MCOPS3; MGC2413; lcc; SRY related HMG box 2;

Immunogen: A synthesized peptide derived from human SOX2

Conjugate: Unconjugated

Modification: Unmodified