SPOP Monoclonal Antibody-MB11629

SPOP Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11629-50, MB11629-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O43791

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SPOP in MCF-7Lysates using SPOP antibody.

Bioworld Molecular Weight: Calculated MW: 42 kDa; Observed MW: 42 kDa

Specificity: IgG

Alternative Name: Speckle-type POZ protein; HIB homolog 1; Roadkill homolog 1

Immunogen: A synthetic peptide of human SPOP

Conjugate: Unconjugated

Modification: Unmodified