SPTLC1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA30009-50, RA30009-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: serine palmitoyltransferase long chain base subunit 1 (SPTLC1) Homo sapiens This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: SPTLC1, LCB1, Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 52 Protein Molecular Weight (kDa): 52 Storage: -20°C/1 year Human Gene ID: 10558 Human SwissProt Number: O15269 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only