SPTLC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11716-20, A11716-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 63kDa
Observed Molecular Weight: 58kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9517
SWISS: O15270
Alternate Names: LCB2; SPT2; HSN1C; LCB2A; NSAN1C; hLCB2a; SPTLC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Cardiovascular, Lipids, Fatty Acids.
NCBI Alias: SPTLC2
Research Use Only