SQSTM1/p62 (Phospho-Ser403) Rabbit Polyclonal Antibody - BT-AP04879

SQSTM1/p62 (Phospho-Ser403) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04879-20, BT-AP04879-50, BT-AP04879-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Research Areas: Epigenetics and nuclear signaling; Cancer; Signal transduction; Cardiovascular; Metabolism

Target Protein: SQSTM1

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SQSTM1/p62

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13501; Mouse: Q64337; Rat: O08623

Synonyms: SQSTM1/p62;Ser403; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62

GeneID: Human: 8878; Mouse: 18412; Rat: 113894

Research Use Only