Product Description

SQSTM1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS80377-50, BS80377-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Enables K63-linked polyubiquitin modification-dependent protein binding activity, identical protein binding activity, and ionotropic glutamate receptor binding activity. Involved in several processes, including brown fat cell proliferation, energy homeostasis, and positive regμlation of long-term synaptic potentiation. Acts upstream of or within negative regμlation of transcription by RNA polymerase II. Located in several cellμlar components, including aggresome, autolysosome, and sperm midpiece. Is expressed in several structures, including alimentary system, central nervous system, genitourinary system, limb, and sensory organ. Used to study Paget's disease of bone. Human ortholog(s) of this gene implicated in GNE myopathy, Paget's disease of bone, and frontotemporal dementia and/or amyotrophic lateral sclerosis-3. Orthologous to human SQSTM1 (sequestosome 1).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Osi, p62, A170, STAP, OSF-6, STONE14

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of mouse SQSTM1(NP_035148.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q64337

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only