SRA Monoclonal Antibody - BT-MCA4205

SRA Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4205-50, BT-MCA4205-100

Citations, Manuals and MSDS Available upon request.

Background: Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.

Research Areas: Others

Target Protein: SRA

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7H1G1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: SRA

Immunogen: Purified recombinant fragment of SRA expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q9HD15

Synonyms: SRAP, STRAA1

GeneID: 10011

Research Use Only