Product Description

SRPK3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62473-50, BS62473-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Arginine/serine-rich (RS) domain-containing proteins and their phosphorylation by specific protein kinases constitute control circuits to regμlate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells. Two SR protein-specific kinases (SRPK, also designated SFRSK), SRPK1 and SRPK2, are highly specific for the phosphorylation of these RS proteins, thereby contributing to splicing regμlation. SRPK1 plays a role in the condensation of sperm chromatin. SRPK2 has a stringent preference for SR dipeptides and contains a proline-rich sequence at its amino terminus. Both SRPK1 and SRPK2 are highly expresed in testes. SRPK1 is found exclusively in pancreas and SRPK2 is found exclusively in brain and lung. SRPK3 is expressed in the heart and in skeletal muscle.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB

Alternate Names: SRSF protein kinase 3, Muscle-specific serine kinase 1, MSSK-1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine/threonine-protein kinase 23, SRPK3, MSSK1, STK23

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human SRPK3.

Dilution: WB:1:500~1:1000

Purification: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Specificity: SRPK3 polyclonal antibody detects endogenous levels of SRPK3 protein.

Molecular Weight: ~ 59 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UPE1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only