Product Description

SRPK3 Polyclonal Antibody

Catalogue Numbers: BS62473-50, BS62473-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9UPE1

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB:1:500~1:1000

Background: Arginine/serine-rich (RS) domain-containing proteins and their phosphorylation by specific protein kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells. Two SR protein-specific kinases (SRPK, also designated SFRSK), SRPK1 and SRPK2, are highly specific for the phosphorylation of these RS proteins, thereby contributing to splicing regulation. SRPK1 plays a role in the condensation of sperm chromatin. SRPK2 has a stringent preference for SR dipeptides and contains a proline-rich sequence at its amino terminus. Both SRPK1 and SRPK2 are highly expresed in testes. SRPK1 is found exclusively in pancreas and SRPK2 is found exclusively in brain and lung. SRPK3 is expressed in the heart and in skeletal muscle.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: SRPK3 polyclonal antibody detects endogenous levels of SRPK3 protein.

Extra Notes: Western blot (WB) analysis of SRPK3 polyclonal antibody at 1:500 dilution
LaneA:PC3 whole cell lysate
LaneB:H1792 whole cell lysate
LaneC:PC12 whole cell lysate
LaneD:The heart tissue lysate of Mouse

Bioworld Molecular Weight: ~ 59 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: SRSF protein kinase 3; Muscle-specific serine kinase 1; MSSK-1; Serine/arginine-rich protein-specific kinase 3; SR-protein-specific kinase 3; Serine/threonine-protein kinase 23; SRPK3; MSSK1; STK23

Immunogen: Synthetic peptide, corresponding to Human SRPK3.

Conjugate: Unconjugated

Modification: Unmodified