Product Description

ST18 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65718-50, BS65718-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ST18 is a 1, 047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cμltured breast cancer cells. ST18 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a resμlt of defects in specific genes that map to chromosome 8.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Horse, Sheep

Host: Rabbit

Applications: WB，FCM，

Alternate Names: KIAA0535, St18, ST18_HUMAN, suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein), Suppression of tumorigenicity 18 protein, Suppression of tumorigenicity protein 18, Zinc finger protein 387, Znf387.  

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human ST18/Znf387:451-550/1047 

Dilution: WB=1:500-2000，Flow-Cyt=1ug/test

Purification: affinity purified by Protein A

Specificity: ST18 Polyclonal Antibody detects endogenous levels of ST18 protein.

Molecular Weight: 110 kD，115 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60284

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only