ST2 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS65587-50, BS65587-100
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Swiss-Prot: Q01638
Host: Rabbit
Reactivity: Mouse,Rat, Dog, Pig, Cow,
Applications: FCM
All Applications: Flow-Cyt=2ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Background: ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.
Purification and Purity: affinity purified by Protein A
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ST2 polyclonal Antibody detects endogenous levels of ST2 protein.
Bioworld Molecular Weight: ~61kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: DER-4; DER4; FIT 1; Growth stimulation expressed gene 2; homolog of mouse growth stimulation-expressed; Il1rl1; IL33R; ILRL1_HUMAN; Interleukin 1 receptor like 1; interleukin 1 receptor related protein; Interleukin-1 receptor-like 1; Ly84; Lymphocyte antigen 84; Protein ST2; ST2; ST2L; ST2V; Ste2; Suppressor of tumorigenicity 2; T1; T1 protein.
Immunogen: KLH conjugated synthetic peptide derived from human Interleukin 1 receptor like 1:11-110/556
Conjugate: Unconjugated
Modification: Unmodified