STAB2 rabbit pAb - ES11201

STAB2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11201-50, ES11201-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300 IF 1:100-300 Not yet tested in other applications.

Reactivity: Human; Rat; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 980-1060

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 280kD

Human Gene ID: 55576

Human SWISS Prot NO: Q8WWQ8

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Only a small amount appears to be present at the cell surface (PubMed:17145755).

Research Use Only