STAT1 mouse Monoclonal Antibody (12E8) - BT-MCA1159

STAT1 mouse Monoclonal Antibody (12E8)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA1159-20, BT-MCA1159-50, BT-MCA1159-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Research Areas: Signal transduction; Epigenetics and nuclear signaling; Cancer; Microbiology

Target Protein: STAT1

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: STAT1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P42224; Mouse: P42225

Synonyms: STAT1

GeneID: Human: 6772

Research Use Only