STAT2 Polyclonal Antibody - RA30105

STAT2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30105-50, RA30105-100

Citations, Manuals and MSDS Available upon request.

Background: signal transducer and activator of transcription 2 (STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000

Alternative Names: STAT2; Signal transducer and activator of transcription 2; p113

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 6773

Protein MW (KDa): 98

SWISS: P52630

Source: Rabbit

Research Use Only