Product Description

Stat2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35074-50, RA35074-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: signal transducer and activator of transcription 2 (STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section)

Alternate Names: STAT2, Signal transducer and activator of transcription 2, p113, YM3416

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.

Molecular Weight: 98

Protein Molecular Weight (kDa): 98

Storage: -20°C/1 year

Human Gene ID: 6773

Human SwissProt Number: P52630

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Research Use Only