Product Description

Stat4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35080-50, RA35080-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: signal transducer and activator of transcription 4 (STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section)

Alternate Names: STAT4, Signal transducer and activator of transcription 4, YM3456

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 86

Protein Molecular Weight (kDa): 86

Storage: -20°C/1 year

Human Gene ID: 6775

Human SwissProt Number: Q14765

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Research Use Only