Product Description

Stat5a Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30134-50, RA30134-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: signal transducer and activator of transcription 5A (STAT5A) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF/ICC, ELISA

Alternate Names: STAT5A, STAT5, Signal transducer and activator of transcription 5A

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 90

Protein Molecular Weight (kDa): 90

Storage: -20°C/1 year

Human Gene ID: 6776

Human SwissProt Number: P42229

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only