STAT6 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91291-50, BS91291-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P42226
Host: Rabbit
Reactivity: Human
Applications: WB, ICC IHC FC
All Applications: WB:1:1,000
ICC:1:200
IHC:1:200
FC:1:100-1:200
Background: In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: STAT6 polyclonal antibody detects endogenous levels of STAT6 protein.
Bioworld Molecular Weight: 94 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of STAT6 on different cell lysates using anti-STAT6 antibody at 1/1000 dilution.
Positive control:
Lane 1: Raji
Lane 2: Daudi
Lane 3: Hela
Lane 4: Ags
Lane 5: Jurkat, ICC staining STAT6 in Hela cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: STAT6, 12S1644, D12S1644, IL 4 STAT, IL-4 Stat, IL4 STAT, Interleukin 4 Induced, Interleukin 4 Induced Transcription Factor IL4 STAT, Signal transducer and activator of transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, Signal transducer and activator of transcription 6, interleukin 4 induced, STAT 6, STAT interleukin4 induced, STAT, interleukin4 induced, Stat6, STAT6, STAT6B, STAT6C, Transcription factor IL 4 STAT,
Immunogen: peptide
Conjugate: Unconjugated
Modification: Unmodified