Product Description

STEAP4 Polyclonal Antibody

Catalogue Numbers: BS61396-50, BS61396-100

Sizes: 50µl, 100µl

Alternative Name: Metalloreductase STEAP4; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; Tumor necrosis factor, alpha-induced protein 9; STEAP4; STAMP2; TNFAIP9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q687X5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: STAMP2 (SixTransMembrane protein of prostate 2), also known as STEAP4 (STEAP family member 4), TIARP or TNFAIP9, is a 459 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one ferric oxidoreductase domain. Expressed ubiquitously with highest expression in lung, prostate, placenta and heart, STAMP2 functions as a metalloreductase that uses FAD as a cofactor to reduce both Fe3+ and Cu2+ to Fe2+ and Cu1+, respectively. Multiple isoforms of STAMP2 exist due to alternative splicing events. The gene encoding STAMP2 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STEAP4 polyclonal antibody detects endogenous levels of STEAP4 protein.

Bioworld Molecular Weight: ~ 52 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of STEAP4 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate(40ug)
Lane 2: NIH-3T3 whole cell lysate(40ug)
Lane 3: H9C2 whole cell lysate(40ug)
Lane 4: Hela whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 195-240 of Human STEAP4.

Conjugate: Unconjugated

Modification: Unmodified