STING (Phospho-Ser366) Rabbit Polyclonal Antibody - RA36798

STING (Phospho-Ser366) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36798-50, RA36798-100

Citations, Manuals and MSDS Available upon request.

Background: transmembrane protein 173 (TMEM173) Homo sapiens This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Condition: Liquid in PBS containing 50% glycerol, and 0.111% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Transmembrane protein 173 (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Stimulator of interferon genes protein) (hSTING)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 340061

Protein MW (KDa): 42

SWISS: Q86WV6

Source: Rabbit

Research Use Only