Product Description

STING/TMEM173 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30559-50, RA30559-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: transmembrane protein 173 (TMEM173) Homo sapiens This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Stimulator of interferon genes protein, hSTING

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 42, 23

Protein Molecular Weight (kDa): 42, 23

Storage: -20°C/1 year

Human Gene ID: 340061

Human SwissProt Number: Q86WV6

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only