STIP1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91297-50, BS91297-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P31948(Human) Q60864(Mouse) O35814(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC FC IP, ICC
All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100
ICC:1:50
Background: Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: STIP1 polyclonal antibody detects endogenous levels of STIP1 protein.
Bioworld Molecular Weight: 63 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of STIP1 on Mouse testis and Rat testis lysates using anti-STIP1 antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-STIP1 antibody. Counter stained with hematoxylin.
Alternative Name: STI1, Hop, STIP1, Epididymis secretory sperm binding protein Li 94n, HEL S 94n, Hop, Hsc70/Hsp90 organizing protein, Hsc70/Hsp90-organizing protein, IEF SSP 3521, NY REN 11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, STIP1, STIP1, Stress induced phosphoprotein 1, Stress-induced-phosphoprotein 1, Transformation sensitive protein IEF SSP 3521, Transformation-sensitive protein IEF SSP 3521,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodified