STIP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1219-20, A1219-100
Citations, Manuals and MSDS Available upon request.
Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 63kDa
Observed Molecular Weight: 63kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 10963
SWISS: P31948
Alternate Names: HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521; STIP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Signal Transduction, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: STIP1
Research Use Only