Product Description

STK31 Polyclonal Antibody

Catalogue Numbers: BS60242-50, BS60242-100

Sizes: 50µl, 100µl

Alternative Name: Serine/threonine-protein kinase 31; Serine/threonine-protein kinase NYD-SPK; Sugen kinase 396; SgK396; SGK396

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9BXU1

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Protein kinases catalyze the post-translational transfer of a phosphate group from ATP to a serine, threonine or tyrosine residue, thereby playing a major role in many intracellular and intercellular signaling cascades. STK31 (Serine/threonine-protein kinase 31) is a 1019 amino acid protein belonging to the protein kinase superfamily. STK31 contains one C-terminal protein kinase domain and one N-terminal Tudor domain, which functions as a protein-protein interaction motif during RNA metabolism or transport. As a testis-specific kinase, STK31 is found in both post-meitoic spermatocytes as well as in mature spermatozoa and is thought to be involved in spermatogensis and/or sperm function. Also, as a result of frequent expression in colorectal, gastric and esophageal cancers, STK31 has been identified as a potential cancer/testis (CT) antigen. There are two named isoforms of STK31 which are produced as a result of an alternative splicing event.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STK31 polyclonal antibody detects endogenous levels of STK31 protein.

Bioworld Molecular Weight: ~ 116 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of STK31 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: PC12 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human STK31.

Conjugate: Unconjugated

Modification: Unmodified