STK36 rabbit pAb - ES5543

STK36 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5543-50, ES5543-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011],

Alternate Name: STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human STK36. AA range:387-436

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 170kD

Human Gene ID: 27148

Human SWISS Prot NO: Q9NRP7

Subcellular Location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Low levels also present in the nucleus.

Research Use Only