STK40 Polyclonal Antibody - E-AB-14693

STK40 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14693-60, E-AB-14693-120, E-AB-14693-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: STK40

Target Synonym: 2310004N11Rik; MGC4796; OTTHUMP00000009948; OTTHUMP00000009951; RP11-268J15.4; Ser/Thr like kinase; Serine/threonine kinase 40; Serine/threonine protein kinase 40; SgK495; SHIK; SINK homologous serine/threonine protein kinase; SINK-homologous inhibitory kinase; STK 40; Sugen kinase 495

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8N2I9

Background: STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human STK40

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only