Product Description

STMN2 Polyclonal Antibody

Catalogue Numbers: BS5948-50, BS5948-100

Sizes: 50µl, 100µl

Alternative Name: Stathmin-2; Stathmin 2; Stathmin2; Superior cervical ganglion-10 protein; Protein SCG10; SCG10; SCGN10

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q93045

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: SCG10, also designated stathmin-like 2 (STMN2), is a neuronal growth-associated protein (nGAP) that belongs to the stathmin family. Stathmin family phosphoproteins are involved in regulation of microtubule dynamics and signal transduction. SCG10, which is membrane- associated and neuron-specific, may participate in neuronal differentiation and may modulate membrane interaction with the cytoskeleton during neurite outgrowth. The SCG10 protein binds to and inhibits the assembly of microtubules, and can also induce microtubule disassembly. The assembly and disassembly of microtubules is necessary for cell division, intracellular transport and cell movements, as well as neurite elongation, outgrowth and branching in the developing nervous system.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: STMN2 polyclonal antibody detects endogenous levels of STMN2 protein.

Bioworld Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of STMN2 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 cell lysate
Lane 2: NIH-3T3 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 134-179 of Human STMN2.

Conjugate: Unconjugated

Modification: Unmodified