Product Description

STRADA Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS71572-50, BS71572-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to resμlt in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Mμltiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their fμll-length nature is not known.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF, FC

Alternate Names: LYK5, PMSE, Stlk, STRAD, NY-BR-96

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to Human STRADA.

Dilution: WB: 1:500~1:1000
ICC/IF: 1:50~1:100
FC: 1:10~1:30

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: STRADA polyclonal antibody detects endogenous levels of STRADA protein.

Molecular Weight: ~ 48 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7RTN6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only