Product Description

Striatin Polyclonal Antibody

Catalogue Numbers: BS5949-50, BS5949-100

Sizes: 50µl, 100µl

Alternative Name: STRN

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43815

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Down-regulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Striatin polyclonal antibody detects endogenous levels of Striatin protein.

Bioworld Molecular Weight: ~ 86, 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Striatin polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: NIH-3T3 cell lysate
Lane 3: PC12 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 708-753 of Human Striatin.

Conjugate: Unconjugated

Modification: Unmodified