STXB2 rabbit pAb - ES12885

STXB2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12885-50, ES12885-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013],

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human STXB2 AA range: 392-442

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 6813

Human SWISS Prot NO: Q15833

Subcellular Location: cytosol, plasma membrane, integral component of membrane, apical plasma membrane, SNARE complex, specific granule, azurophil granule, zymogen granule membrane, cytolytic granule, extracellular exosome, tertiary granule,

Research Use Only