SUN2 Polyclonal Antibody-BS9957M

SUN2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9957M-50, BS9957M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UH99

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF FC

All Applications: WB: 1:500-1:2000 IHC: 1:50-1:200
FC: 1:50-1:100 ICC/IF: 1:50-1:100

Background: SUN2 (sad1/unc-84 protein-like 2), also known as UNC84B (unc-84 homolog B), FRIGG, KIAA0668 or RAB5IP, is a 717 amino acid single-pass membrane protein that contains one SUN domain and localizes to the membrane of both the nucleus and the endosome. Widely expressed in a variety of tissues, including lung, muscle and heart, SUN2 interacts with Rab 5A and may play a role in homotypic endosome fusion. The gene encoding SUN2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.

Purification and Purity: Protein A affinity purified.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of SUN2 and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SUN2 on rat kidney tissue lysate using anti-SUN2 antibody at 1:2000 dilution., Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-SUN2 antibody. Counter stained with hematoxylin., Flow cytometric analysis of SK-Br-3 cells with SUN2 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Alternative Name: SUN domain-containing protein 2; Protein unc-84 homolog B; Rab5-interacting protein; Rab5IP; Sad1/unc-84 protein-like 2; SUN2; FRIGG; KIAA0668; RAB5IP; UNC84B

Immunogen: Recombinant protein within human SUN2 aa 500-700.

Conjugate: Unconjugated

Modification: Unmodified