Product Description

Survivin Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22112-60, E-AB-22112-120, E-AB-22112-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Survivin

Target Synonym: API4; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; Apoptosis inhibitor4; Baculoviral IAP repeat containing 5; Baculoviral IAP repeat containing protein 5; Baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; BIRC5; EPR 1; IAP4; Survivin variant 3 alpha; SVV; TIAP

Research Areas: Cancer, Cell Biology, Neuroscience

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Rat

Application: WB, IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:4E2

UNIProt ID: O15392

Background: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:1000-2000, IHC 1:50-1:200

Observed MW: 16kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only