SV2A Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65592-50, BS65592-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. The highest expression levels were observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bμlb. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimμlated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters. Category: Primary Antibody Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit Host: Rabbit Applications: FCM Alternate Names: Synaptic vesicle protein 2A, Synaptic vesicle glycoprotein 2A, Synaptic vesicle protein 2A, Synaptic vesicle protein 2, Sv2, Kiaa0736, SV2A_HUMAN. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human SV2A:451-550/743 Dilution: Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations shoμld be determined by the end user. Purification: affinity purified by Protein A Specificity: SV2A polyclonal Antibody detects endogenous levels of SV2A protein. Molecular Weight: ~83kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q7L0J3 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only