SV2C rabbit pAb - ES3807

SV2C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3807-50, ES3807-100

Citations, Manuals and MSDS Available upon request.

Background: function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles., PTM:N-glycosylated., similarity:Belongs to the major facilitator superfamily., subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas., subunit:Interacts with SYT1 in a calcium-dependent manner.,

Alternate Name: SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from the Internal region of human SV2C.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 82kD

Human Gene ID: 22987

Human SWISS Prot NO: Q496J9

Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.

Research Use Only