SV40 T Antigen Monoclonal Antibody-MB12265

SV40 T Antigen Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12265-50, MB12265-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P03070

Host: Rabbit

Reactivity: All

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 82 kDa; Observed MW: 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SV40 Tantigen in A549, HL-60, U251 lysates using SV40 T Antigen antibody., Immunocytochemistry analysis of SV40 Tantigen in hela using SV40 Tantigen antibody, and DAPI

Alternative Name: Large T antigen; LT; LT-AG

Immunogen: A synthetic peptide of SV40 T-antigen

Conjugate: Unconjugated

Modification: Unmodified